Associate Director, Discovery (Carmine Singapore)

Job Location



Carmine Therapeutics is an Esco Ventures X company pioneering a powerful new class of drugs based on

engineered red blood cells extracellular vesicles (RBCEVs), founded by Esco Ventures and Professors

Harvey Lodish, Minh Le and Jiahai Shi. Carmine’s proprietary Red Cell EV Gene Therapy (REGENTTM)

platform is positioned to address some of the technological unmet needs related to the delivery of next

generation therapeutic modalities such as nucleic acids. Carmine was awarded the 2019 Bristol-Myers

Squibb’s Golden Ticket to LabCentral (Cambridge, MA) and has established a research collaboration with

Takeda Pharmaceuticals in a deal worth over $900M USD. The company is well-capitalized to develop

next generation non-viral gene therapies that would overcome most of the limitations of AAV-based

gene therapy. Carmine is based both in Cambridge, MA as well as Singapore.

The Discovery Team in Carmine Singapore is looking for an Associate Director to contribute to R&D

program development. Reporting to the VP of Discovery, the incumbent will co-lead a team and drive

discovery projects through close collaboration with others to expand our pipeline of non-viral gene


Key Duties & Responsibilities

  • Design experimental plans in coordination with research objectives of the Discovery team

  • Assist in the recruitment, oversight, and mentoring of a team of scientists and research associates to ensure smooth R&D operations within the team

  • Stays abreast of the latest scientific and competitive developments and applying knowledge to team strategy and pipeline expansion

  • Regularly communicates results to project teams and senior leadership; prepares presentations, reports, patent filings and external communications as required

  • Contributes to building a culture that embraces scientific excellence and integrity with a sense of urgency and collaboration with key stakeholders

  • Maintain and manage external research relationships with academic and/ or commercial partners

  • Support the continued creation and expansion of company’s intellectual property

  • Perform other related duties incidental to the work described herein


  • An experienced biologist with a Ph.D. in immunology, cell biology, molecular biology or a related scientific discipline

  • Minimum 7 years of experience in biological sciences research in an academic or industry setting

  • Demonstrated record of success with strong publication record or patent filings

  • Experience in leading biology and cross-functional teams

  • Knowledge of gene therapy/nucleic acid delivery/extracellular vesicles is an advantage

  • Team oriented, highly motivated, execution-focused with strong work ethic, ability to thrive in an entrepreneurial and multidisciplinary environment

Interested candidates, please submit a CV to

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