Senior Scientist (Protein Biochemistry) - CLOSED

Job Description

Carmine Therapeutics is an Esco Ventures X company pioneering a powerful new class of drugs based on engineered red blood cells extracellular vesicles (RBCEVs), founded by Esco Ventures and Professors Harvey Lodish, Minh Le and Jiahai Shi. Carmine focuses on developing a therapeutic platform that would address some of the technological unmet needs related to the delivery of next generation therapies such as nucleic acid-based therapeutics. Carmine has assembled a stellar scientific advisory board and is well-capitalized to develop first-in-class therapies against genetic diseases. Carmine will be based in Singapore but also with operations in Cambridge, Massachusetts.

Carmine is looking for a Senior Scientist to join us in this exciting venture. An ideal candidate is one who is independent, technically competent, and able to work efficiently across multiple projects. Individuals with PhD in protein biochemistry are preferred. This role may involve a job posting to Cambridge, Massachusetts and therefore candidates should ideally be Singaporeans or US citizens.


  • Perform independent research work through the design, execution and troubleshoot of experiments

  • Manage studies performed by contract research organizations

  • Evaluate and interpret collected data and prepare oral presentations or written reports/ scientific manuscripts/literature for publication. Present data from research work internally and externally.

  • Contribute to scientific and strategy discussions to achieve R&D milestones

  • Perform technology transfer to R&D establishment in Cambridge, Massachusetts.

  • Maintain accurate and detailed documentation of research data, inventories, protocols, maintenance logs, sample processing logs, SOPs etc.

  • Lab management duties including procurement, maintaining equipment wellbeing by timely scheduling of maintenance/ servicing/ calibration.

  • Support the continued protection, creation, and expansion of company’s intellectual property.

  • Perform other related duties incidental to the work described herein.

Job Requirements

  • PhD in protein biochemistry

  • Minimum 3 years of work experience in recombinant protein/antibody expression and purification, and proficiency in relevant molecular biology techniques

  • Proficiency in vector engineering and/or familiarity with the use of genome editing tools (ZFN, TALEN, CRISPR) will be an advantage

  • General laboratory techniques that include flow cytometry, molecular assays (such as qPCR, ELISAs, western blot), histology & microscopy, in vivo animal experiments 

  • Able to manage and ensure smooth operations in the lab

  • Able to work in a fast-paced startup environment

  • Energetic, highly motivated, collaborative


Interested candidates, please submit a CV to Please forward your enquiries to  

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An Esco Ventures X company